Vendor-agnostic · Evidence-led
Precision Human Optimization
Unlock your biological potential with data-driven protocols, evidence-based compounds, and elite longevity strategies. We decode the science of high performance so you can engineer a resilient, optimized life.
- Articles
- 75+
- Compounds
- 50+
- Live tools
- 7
Step 1 / Know your baseline
You can't manage what you don't measure.
Before adding any compound or protocol, get your numbers. The Levine PhenoAge calculator gives you a biological-age estimate from a routine bloodwork panel; the bloodwork tracker shows you which markers sit in the longevity-optimal band versus the standard lab reference range; and the marker articles explain what drives each one up or down.
Protocols
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Alpha-GPC Dosage: 300, 600, or 1,200 mg? Evidence Map
Alpha-GPC dosage by goal: 300-600 mg/day for cognitive enhancement, 600 mg pre-training for power output, 1,200 mg/day for vascular cognitive impairment.
Ashwagandha and L-Theanine: Stack for Stress + Focus
Ashwagandha + L-theanine stack: ashwagandha 300-600 mg/day for chronic stress, L-theanine 100-200 mg as needed for acute focus.
Best Longevity Supplements: Evidence-Tiered, Vendor-Agnostic
The longevity supplements with real human evidence: omega-3, vitamin D3+K2, magnesium glycinate, creatine. Tier-A foundation; Tier-B emerging.
Best Supplements for Men Over 40: Tier-Ranked Guide
Best supplements for men over 40: tier-A foundation (creatine, omega-3, vitamin D3+K2, magnesium), plus age-specific picks (CoQ10 if on statins, ashwagandha.
BPC-157 Dosage: Injection, Oral, Cycling Protocol
BPC-157 dosage protocols compared: 250-500 mcg/day subcutaneous (most-replicated preclinical), 500 mcg twice daily oral for gut-localized use, 4-6 week.
Average Grip Strength: Norms, Targets, How to Improve
Average grip strength by age and sex, with longevity-tier targets. Men 40-54: average ~110-130 lbs, longevity-optimal 145+.
How to Lengthen Telomeres: Diet, Exercise, What's Real
How to lengthen telomeres: lifestyle interventions (diet, exercise, stress reduction) have the strongest evidence (Ornish 2008).
How to Take Creatine Monohydrate: Dose, Timing, Loading
How to take creatine monohydrate: 5 g/day continuous, no cycling, optional 20 g/day loading. Timing barely matters. With or without food.
NSDR (Non-Sleep Deep Rest): Protocol, Evidence, Timing
NSDR (non-sleep deep rest) is the parasympathetic-shift practice popularized by Andrew Huberman, derived from yoga nidra.